Pedersen L, Palshof T
[Pharmaceutical treatment of cancer-associated fatique - review of a Cochrane review.] [JOURNAL ARTICLE]
Ugeskr Laeger 2009 Sep 21; 171(39):2830-2833.
The data and the conclusions of the Cochrane review of drug therapy for the management of cancer related fatique (CRF) is analysed and summarized in this report. Overall, data is weakened substantially by a high degree of heterogeneity that stems primarily from the fact that fatique is a subjective and multidimensional phenomenon Apart from erythropoetin and to some degree methylphenidate, there is no evidence that pharmacologic intervention may reduce CRF. CRF has major impact on quality of life for most patients suffering from a cancer disease. It is therefore of obvious importance to increase the focus on CRF - both in the pharmaceutical industry and in the professional -medical environment.
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